Single versus multiple embryo transfer in successful role of ‎pregnancy at AL Amal IVF Center -Misrata

Document Type : Cohort and Case-Control Studies

Authors

Al Amal IVF Center - Misrata

Abstract

Abstract
This study evaluates the effectiveness of single embryo transfer (SET) versus double ‎embryo transfer (DET) in in vitro fertilization (IVF) and intracytoplasmic sperm injection ‎‎(ICSI) cycles at AL Amal IVF Center, Misrata.‎

Objective ‎
To compare live birth rates (LBR) and pregnancy outcomes between the two methods. ‎

Methods:‎
‎ A retrospective analysis of 1,000 women undergoing IVF/ICSI was conducted.

Results ‎
Indicate that SET had a higher LBR (76.1%) compared to DET (65.2%), with a 10.9% ‎increase in success rates. Additionally, SET was associated with fewer complications, ‎including lower risks of preterm labor (3.8% vs. 13.8%), intrauterine fetal death (0.5% ‎vs. 2.2%), and congenital anomalies (0% vs. 1.2%).Statistical analysis revealed no ‎significant relationship between pregnancy rates and age groups (p-value = 0.610), ‎although older women had lower LBRs, particularly in the DET group. Cost-‎effectiveness analysis demonstrated that SET led to lower medical expenses due to ‎reduced neonatal intensive care unit (NICU) admissions and maternal complications.‎

Conclusion:‎
The study supports the shift towards SET as the preferred approach, even for older ‎women, when good-quality blastocysts are available.‎ While SET minimizes the risks associated with multiple pregnancies, further research ‎is needed to optimize cost-effectiveness strategies. The findings emphasize the ‎benefits of SET in improving perinatal outcomes while maintaining high success rates, ‎reinforcing its role as a superior IVF strategy.‎

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