Oocyte accumulation in low-ovarian reserve women: do or not to do?

Document Type : Mini review

Authors

1 Obstetrics and Gynecology department, Faculty of Medicine, Alexandria University, Egypt.

2 Egyptian Foundation of Reproductive Medicine and Embryology (EFRE), Egypt.

Abstract

Ovarian Poor responder women could be defined as those who have a small number of follicles, usually less than three follicles retrieved after one cycle of ovarian stimulation. Poor responders were classified over time in multiple ways, from the Bologna classification to the recent POSEIDON groups. The oocyte accumulation technique could greatly help poor responder cases; the more oocytes could be retrieved, the better the results are regarding success rates or different tests that need to be done to have euploid-healthy embryos. Going through different studies regarding such an important topic could be a game changer as regards studying the effect of old age on ovarian stimulation, choosing suitable stimulation protocols, managing the outcome of ART through excluding aneuploid embryos, and having enough embryos for that. So, the keyword would be ACCUMULATION, especially for candidates for PGT-A, which can be obtained through repeated stimulation cycles using a cost-effective method such as progesterone primed protocol.

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